MED15, mediator complex subunit 15

MED15, mediator complex subunit 15

• The protein encoded by this gene is a subunit of the multiprotein complexes PC2 and ARC/DRIP and may function as a transcriptional coactivator in RNA polymerase II transcription. This gene contains stretches of trinucleotide repeats and is located in the chromosome 22 region which is deleted in DiGeorge syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]

• Gene Synonyms (mediator of RNA polymerase II transcription subunit 15, CTG repeat protein 7a, PC2 (positive cofactor 2, multiprotein complex) glutamine/Q-rich-associated protein, PC2 glutamine/Q-rich-associated protein, PC2-glutamine-rich-associated protein, TPA inducible gene-1, TPA inducible protein, TPA-inducible gene 1 protein, activator-recruited cofactor 105 kDa component, activator-recruited cofactor, 105-kD, positive cofactor 2, glutamine/Q-rich-associated protein, trinucleotide repeat containing 7, trinucleotide repeat-containing gene 7 protein, ARC105, CAG7A, CTG7A, PCQAP, TIG-1, TIG1, TNRC7,)
• NCBI Gene ID: 51586
• Species: Homo sapiens (Human)
• UNIPROT ID#>>G3V1P5
  UNIPROT ID#>>Q96RN5
  UNIPROT ID#>>B7Z2H7
  UNIPROT ID#>>Q6PKB8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

mediator complex subunit 15 interacts with:

• aldehyde dehydrogenase 8 family member A1
  autophagy related 16 like 1
  elongator acetyltransferase complex subunit 3
  F-box and WD repeat domain containing 7
  INO80 complex ATPase subunit
  INO80 complex subunit D
  integrator complex subunit 9
  mediator complex subunit 10
  mediator complex subunit 11
  mediator complex subunit 18
  mediator complex subunit 19
  mediator complex subunit 25
  mediator complex subunit 28
  mediator complex subunit 29
  mediator complex subunit 8
  mediator complex subunit 9
  PAF1 homolog, Paf1/RNA polymerase II complex component
  tripartite motif containing 11

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.