ARID4B, AT-rich interaction domain 4B

ARID4B, AT-rich interaction domain 4B

• This gene encodes a protein with sequence similarity to retinoblastoma-binding protein-1. The encoded protein is a subunit of the histone deacetylase-dependant SIN3A transcriptional corepressor complex, which functions in diverse cellular processes including proliferation, differentiation, apoptosis, oncogenesis, and cell fate determination. The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]

• Gene Synonyms (AT-rich interactive domain-containing protein 4B, 180 kDa Sin3-associated polypeptide, ARID domain-containing protein 4B, AT rich interactive domain 4B (RBP1-like), Rb-binding protein homolog, SIN3A-associated protein 180, breast cancer-associated antigen 1, breast cancer-associated antigen BRCAA1, breast carcinoma-associated antigen, histone deacetylase complex subunit SAP180, retinoblastoma-binding protein 1-like 1, sin3-associated polypeptide p180, BCAA, BRCAA1, RBBP1L1, RBP1L1, SAP180,)
• NCBI Gene ID: 51742
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R3R1
  UNIPROT ID#>>Q4LE39
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

AT-rich interaction domain 4B interacts with:

• aurora kinase A interacting protein 1
  dynein axonemal assembly factor 6
  ELL associated factor 1
  F-box and WD repeat domain containing 7
  forkhead box K1
  GATA zinc finger domain containing 1
  laccase domain containing 1
  MAX dimerization protein 3
  NHS like 2
  N-terminal glutamine amidase 1
  PHD finger protein 23
  pleckstrin homology and FYVE domain containing 2
  proline rich 23B
  PTGES3L-AARSD1 readthrough
  SDS3 homolog, SIN3A corepressor complex component
  Sin3A associated protein 130
  SIN3-HDAC complex associated factor
  SIN3-HDAC complex associated factor
  SPANX family member B1
  TNFAIP3 interacting protein 2
  zinc finger protein 704

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.