MXD3, MAX dimerization protein 3

MXD3, MAX dimerization protein 3

• This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.[provided by RefSeq, Dec 2008]

• Gene Synonyms (max dimerization protein 3, Max-associated protein 3, Max-interacting transcriptional repressor MAD3, class C basic helix-loop-helix protein 13, max dimerizer 3, BHLHC13, MAD3, MYX,)
• NCBI Gene ID: 83463
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9BW11
  UNIPROT ID#>>A0A024R7S0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

MAX dimerization protein 3 interacts with:

• assembly factor for spindle microtubules
  BRMS1 like transcriptional repressor
  cysteine rich tail 1
  keratin associated protein 10-7
  keratin associated protein 3-3
  NBPF member 19
  notch 2 N-terminal like A

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.