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RNF216, ring finger protein 216

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RNF216, ring finger protein 216

  • This gene encodes a cytoplasmic protein which specifically colocalizes and interacts with the serine/threonine protein kinase, receptor-interacting protein (RIP). Zinc finger domains of the encoded protein are required for its interaction with RIP and for inhibition of TNF- and IL1-induced NF-kappa B activation pathways. The encoded protein may also function as an E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes and transfers it to substrates. Several alternatively spliced transcript variants have been described for this locus but the full-length natures of only some are known. [provided by RefSeq, Jul 2008]

  • Gene Synonyms (E3 ubiquitin-protein ligase RNF216, RING-type E3 ubiquitin transferase RNF216, triad domain-containing protein 3, ubiquitin-conjugating enzyme 7-interacting protein 1, zinc finger protein inhibiting NF-kappa-B, CAHH, TRIAD3, U7I1, UBCE7IP1, ZIN,)
  • NCBI Gene ID: 54476
  • Species: Homo sapiens (Human)
  • UNIPROT ID#>>A8K8N1
    UNIPROT ID#>>Q9NWF9
  • View the NCBI Database for this Gene »

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ring finger protein 216 interacts with:

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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