TICAM1, toll like receptor adaptor molecule 1

TICAM1, toll like receptor adaptor molecule 1

• This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. This protein is involved in native immunity against invading pathogens. It specifically interacts with toll-like receptor 3, but not with other TLRs, and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B, during an antiviral immune response. [provided by RefSeq, Jan 2012]

• Gene Synonyms (IIAE6, MyD88-3, PRVTIRB, TICAM-1, TRIF, TIR domain-containing adapter molecule 1, TIR domain containing adaptor inducing interferon-beta, TIR domain-containing adapter protein inducing IFN-beta, proline-rich, vinculin and TIR domain-containing protein B, putative NF-kappa-B-activating protein 502H, toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta,)
• NCBI Gene ID: 148022
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8IUC6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

toll like receptor adaptor molecule 1 interacts with:

• toll like receptor adaptor molecule 1
  toll like receptor adaptor molecule 2

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