PAF1, PAF1 homolog, Paf1/RNA polymerase II complex component

PAF1, PAF1 homolog, Paf1/RNA polymerase II complex component

• This gene encodes a subunit of the polymerase associated factor (PAF1) complex. The PAF1 complex interacts with RNA polymerase II and plays a role in transcription elongation as well as histone modifications including ubiquitylation and methylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]

• Gene Synonyms (RNA polymerase II-associated factor 1 homolog, Paf1, RNA polymerase II associated factor, homolog, pancreatic differentiation protein 2, F23149_1, PD2,)
• NCBI Gene ID: 54623
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8N7H5
  UNIPROT ID#>>A0A024R0H6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

PAF1 homolog, Paf1/RNA polymerase II complex component interacts with:

• cell division cycle 73
  elongator acetyltransferase complex subunit 3
  heterogeneous nuclear ribonucleoprotein L like
  integrator complex subunit 9
  LEO1 homolog, Paf1/RNA polymerase II complex component
  lysine acetyltransferase 8
  mediator complex subunit 8
  MSL complex subunit 1
  MSL complex subunit 2
  myosin heavy chain 14
  pleckstrin homology domain containing A4
  polyhomeotic homolog 3
  pyrin and HIN domain family member 1
  regulation of nuclear pre-mRNA domain containing 1B
  ring finger protein 20
  THO complex 2
  TOX high mobility group box family member 4
  WD repeat domain 61
  WD repeat domain 61

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.