RNF125, ring finger protein 125

RNF125, ring finger protein 125

• This gene encodes a novel E3 ubiquitin ligase that contains a RING finger domain in the N-terminus and three zinc-binding and one ubiquitin-interacting motif in the C-terminus. As a result of myristoylation, this protein associates with membranes and is primarily localized to intracellular membrane systems. The encoded protein may function as a positive regulator in the T-cell receptor signaling pathway. [provided by RefSeq, Mar 2012]

• Gene Synonyms (E3 ubiquitin-protein ligase RNF125, T-cell RING activation protein 1, T-cell ring protein identified in activation screen, ring finger protein 125, E3 ubiquitin protein ligase, TNORS, TRAC-1, TRAC1,)
• NCBI Gene ID: 54941
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q96EQ8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ring finger protein 125 interacts with:

• basic helix-loop-helix family member a9
  checkpoint with forkhead and ring finger domains
  EF-hand domain containing 1
  fibronectin type III domain containing 11
  myozenin 3
  PNMA family member 6A
  polycomb group ring finger 1
  ring finger protein 125
  tripartite motif containing 46
  ubiquitin conjugating enzyme E2 U
  ubiquitin conjugating enzyme E2 W
  zinc finger protein 414

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.