INTS11, integrator complex subunit 11

INTS11, integrator complex subunit 11

• The Integrator complex contains at least 12 subunits and associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates the 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690). INTS11, or CPSF3L, is the catalytic subunit of the Integrator complex (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008]

• Gene Synonyms (integrator complex subunit 11, CPSF3-like protein, cleavage and polyadenylation specific factor 3-like, cleavage and polyadenylation-specific factor 3-like protein, protein related to CPSF subunits of 68 kDa, related to CPSF subunits 68 kDa, CPSF3L, CPSF73L, INT11, RC-68, RC68,)
• NCBI Gene ID: 54973
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R073
  UNIPROT ID#>>A0A087WYI0
  UNIPROT ID#>>A0A024R0F2
  UNIPROT ID#>>Q5TA45
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

integrator complex subunit 11 interacts with:

• chromosome 1 open reading frame 94
  COBW domain containing 1
  coiled-coil domain containing 120
  family with sequence similarity 222 member B
  integrator complex subunit 10
  integrator complex subunit 14
  integrator complex subunit 2
  integrator complex subunit 3
  integrator complex subunit 4
  integrator complex subunit 4
  integrator complex subunit 5
  integrator complex subunit 9
  keratin associated protein 15-1
  keratin associated protein 26-1
  leukocyte receptor cluster member 8
  nucleic acid binding protein 1
  oxoeicosanoid receptor 1
  phospholipid scramblase 4
  proline rich 35
  Spi-C transcription factor
  VAC14 component of PIKFYVE complex
  yippee like 3
  zinc finger CCCH-type containing 10

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.