INTS3, integrator complex subunit 3

INTS3, integrator complex subunit 3

• The protein encoded by this gene can form a complex with human single-strand DNA binding proteins 1 or 2 (hSSB1 and hSSB2) and other proteins to mediate genome stability and the DNA damage response. The encoded protein is also part of a multiprotein complex that interacts with the C-terminal domain of RNA polymerase II large subunit to help regulate processing of U1 and U2 small nuclear RNAs. [provided by RefSeq, May 2016]

• Gene Synonyms (integrator complex subunit 3, SOSS complex subunit A, sensor of single-strand DNA complex subunit A, sensor of ssDNA subunit A, C1orf193, C1orf60, INT3, SOSS-A, SOSSA,)
• NCBI Gene ID: 65123
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q68E01
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

integrator complex subunit 3 interacts with:

• ATR interacting protein
  catechol-O-methyltransferase domain containing 1
  chromosome 7 open reading frame 26
  copine 2
  integrator complex subunit 14
  integrator complex subunit 3
  integrator complex subunit 4
  integrator complex subunit 5
  integrator complex subunit 6 like
  LEO1 homolog, Paf1/RNA polymerase II complex component
  nuclear apoptosis inducing factor 1
  nucleic acid binding protein 2
  RNA polymerase II associated protein 2
  SIGLEC family like 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.