CDCA8, cell division cycle associated 8

CDCA8, cell division cycle associated 8

• This gene encodes a component of the chromosomal passenger complex. This complex is an essential regulator of mitosis and cell division. This protein is cell-cycle regulated and is required for chromatin-induced microtubule stabilization and spindle formation. Alternate splicing results in multiple transcript variants. Pseudgenes of this gene are found on chromosomes 7, 8 and 16. [provided by RefSeq, Apr 2013]

• Gene Synonyms (borealin, Dasra B, cell division cycle-associated protein 8, dasra-B, hDasra-B, pluripotent embryonic stem cell-related gene 3 protein, BOR, BOREALIN, DasraB, MESRGP,)
• NCBI Gene ID: 55143
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q53HL2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

cell division cycle associated 8 interacts with:

• cell division cycle associated 8
  centromere protein M
  F-box protein 17
  H3 clustered histone 14
  homeobox containing 1
  NEDD1 gamma-tubulin ring complex targeting factor
  NKAP domain containing 1
  NOP9 nucleolar protein
  nucleoporin 43
  PIH1 domain containing 2
  pleckstrin homology domain containing A4
  regulation of nuclear pre-mRNA domain containing 1B
  regulator of chromosome condensation 2
  ribosomal RNA processing 1 homolog B (S. cerevisiae)
  SCY1 like pseudokinase 1
  shugoshin 1
  shugoshin 2
  SPANX family member N2
  TNFAIP3 interacting protein 2
  tubulin beta class I

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.