UBR7, ubiquitin protein ligase E3 component n-recognin 7

UBR7, ubiquitin protein ligase E3 component n-recognin 7

• This gene encodes a UBR box-containing protein that belongs to the E3 ubiquitin ligase family. The protein also contains a plant homeodomain (PHD) in the C-terminus. In mammals, the encoded protein recognizes N-degrons, the destabilizing N-terminal residues of short-lived proteins, which results in ubiquitinylation, and proteolysis via the proteasome. [provided by RefSeq, Jul 2016]

• Gene Synonyms (putative E3 ubiquitin-protein ligase UBR7, N-recognin-7, RING-type E3 ubiquitin transferase UBR7, ubiquitin protein ligase E3 component n-recognin 7 (putative), C14orf130,)
• NCBI Gene ID: 55148
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8N806
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ubiquitin protein ligase E3 component n-recognin 7 interacts with:

• 2-oxoglutarate and iron dependent oxygenase domain containing 1
  atypical chemokine receptor 3
  DET1 and DDB1 associated 1
  developmental pluripotency associated 4
  egl-9 family hypoxia inducible factor 3
  H3 clustered histone 15
  lactate dehydrogenase D
  MRG domain binding protein
  nucleoporin 43
  pleckstrin homology domain containing A4
  protein arginine methyltransferase 6
  RPA interacting protein
  SLX1 homolog A, structure-specific endonuclease subunit
  spindlin family member 2B
  TatD DNase domain containing 1
  ubiquilin 4
  VPS33A core subunit of CORVET and HOPS complexes
  zinc finger and SCAN domain containing 10

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.