PPP6R3, protein phosphatase 6 regulatory subunit 3

PPP6R3, protein phosphatase 6 regulatory subunit 3

• Protein phosphatase regulatory subunits, such as SAPS3, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS3 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 612725) (Stefansson and Brautigan, 2006 [PubMed 16769727]).[supplied by OMIM, Nov 2010]

• Gene Synonyms (C11orf23, PP6R3, SAP190, SAPL, SAPLa, SAPS3, serine/threonine-protein phosphatase 6 regulatory subunit 3, SAPS domain family, member 3, sporulation-induced transcript 4-associated protein SAPL,)
• NCBI Gene ID: 55291
• Species: Homo sapiens (Human)
• UNIPROT ID#>>H7BXH2
  UNIPROT ID#>>A0A024R5F3
  UNIPROT ID#>>Q5H9R7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

protein phosphatase 6 regulatory subunit 3 interacts with:

• acyl-CoA dehydrogenase family member 11
  ankyrin repeat domain 28
  ankyrin repeat domain 44
  ankyrin repeat domain 52
  centrosomal protein 19
  centrosomal protein 44
  DExD/H-box helicase 60
  DnaJ heat shock protein family (Hsp40) member C11
  dual specificity phosphatase 15
  egl-9 family hypoxia inducible factor 3
  ENAH actin regulator
  glycoprotein hormone subunit alpha 2
  histone deacetylase 11
  hook microtubule tethering protein 3
  hypoxia inducible factor 1 subunit alpha inhibitor
  integrin alpha FG-GAP repeat containing 1
  limb development membrane protein 1 like
  MOB kinase activator 1B
  NOP2/Sun RNA methyltransferase 5
  protein phosphatase 6, catalytic subunit
  protein tyrosine phosphatase domain containing 1
  serine/threonine kinase 40
  TOR signaling pathway regulator
  ubiquitin specific peptidase 36
  unk zinc finger
  zinc and ring finger 2
  zinc finger and BTB domain containing 38
  zinc finger protein 746

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.