USP36, ubiquitin specific peptidase 36

USP36, ubiquitin specific peptidase 36

• This gene encodes a member of the peptidase C19 or ubiquitin-specific protease family of cysteine proteases. Members of this family remove ubiquitin molecules from polyubiquitinated proteins. The encoded protein may deubiquitinate and stabilize the transcription factor c-Myc, also known as MYC, an important oncoprotein known to be upregulated in most human cancers. The encoded protease may also regulate the activation of autophagy. This gene exhibits elevated expression in some breast and lung cancers. [provided by RefSeq, Mar 2016]

• Gene Synonyms (DUB1, ubiquitin carboxyl-terminal hydrolase 36, deubiquitinating enzyme 36, ubiquitin specific protease 36, ubiquitin thioesterase 36, ubiquitin-specific-processing protease 36,)
• NCBI Gene ID: 57602
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R8V6
  UNIPROT ID#>>Q9P275
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ubiquitin specific peptidase 36 interacts with:

• ankyrin repeat domain 52
  lin-28 homolog B
  MPN domain containing
  nucleoporin 85
  NudC domain containing 1
  praja ring finger ubiquitin ligase 1
  PTEN induced kinase 1
  SNF2 histone linker PHD RING helicase
  WD repeat domain 36

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.