MAVS, mitochondrial antiviral signaling protein

MAVS, mitochondrial antiviral signaling protein

• This gene encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral immunity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

• Gene Synonyms (CARDIF, IPS-1, IPS1, VISA, mitochondrial antiviral-signaling protein, CARD adapter inducing interferon beta, CARD adaptor inducing IFN-beta, IFN-B promoter stimulator 1, interferon beta promoter stimulator protein 1, putative NF-kappa-B-activating protein 031N, virus-induced signaling adaptor, virus-induced-signaling adapter,)
• NCBI Gene ID: 57506
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q7Z434
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

mitochondrial antiviral signaling protein interacts with:

• CDGSH iron sulfur domain 3
  cytochrome c oxidase assembly factor COX14
  F-box protein 32
  HECT domain E3 ubiquitin protein ligase 3
  interferon induced with helicase C domain 1
  itchy E3 ubiquitin protein ligase
  Josephin domain containing 2
  microtubule associated protein 1 light chain 3 alpha
  mindbomb E3 ubiquitin protein ligase 2
  mitochondrial antiviral signaling protein
  mitochondrial E3 ubiquitin protein ligase 1
  Nedd4 family interacting protein 1
  NLR family member X1
  nucleoporin 35
  OTU deubiquitinase, ubiquitin aldehyde binding 2
  potassium channel tetramerization domain containing 10
  ring finger protein 166
  ring finger protein 34
  sideroflexin 1
  SMAD specific E3 ubiquitin protein ligase 2
  solute carrier family 39 member 12
  stimulator of interferon response cGAMP interactor 1
  toll like receptor adaptor molecule 1
  TRAF3 interacting protein 3
  tripartite motif containing 40
  tripartite motif-containing 31
  ubiquitin specific peptidase 12
  ubiquitin specific peptidase 28
  ubiquitin specific peptidase 29
  ubiquitin specific peptidase 35
  ubiquitin specific peptidase 46
  WD repeat domain 82
  zinc finger CCCH-type containing 12A

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.