FNIP2, folliculin interacting protein 2

FNIP2, folliculin interacting protein 2

• This gene encodes a protein that binds to the tumor suppressor folliculin and to AMP-activated protein kinase (AMPK), and may play a role cellular metabolism and nutrient sensing by regulating the AMPK-mechanistic target of rapamycin signaling pathway. The encoded protein may also be involved in regulating the O6-methylguanine-induced apoptosis signaling pathway. This gene has a closely related paralog that encodes a protein with similar binding activities. Both related proteins also associate with the molecular chaperone heat shock protein-90 (Hsp90) and negatively regulate its ATPase activity and facilitate its association with folliculin. [provided by RefSeq, Jul 2017]

• Gene Synonyms (FNIPL, MAPO1, folliculin-interacting protein 2, FNIP1-like protein, O6-methylguanine-induced apoptosis 1 protein,)
• NCBI Gene ID: 57600
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9P278
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

folliculin interacting protein 2 interacts with:

• folliculin
  folliculin interacting protein 1
  folliculin interacting protein 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.