FNIP1, folliculin interacting protein 1

FNIP1, folliculin interacting protein 1

• This gene encodes a protein that binds to the tumor suppressor protein folliculin and to AMP-activated protein kinase (AMPK). The encoded protein participates in the regulation of cellular metabolism and nutrient sensing by modulating the AMPK and target of rapamycin signaling pathways. This gene has a closely related paralog that encodes a protein with similar binding activities. Both related proteins also associate with the molecular chaperone heat shock protein-90 (Hsp90) and negatively regulate its ATPase activity and facilitate its association with folliculin. [provided by RefSeq, Jul 2017]

• Gene Synonyms (folliculin-interacting protein 1,)
• NCBI Gene ID: 96459
• Species: Homo sapiens (Human)
• UNIPROT ID#>>J3KNG8
  UNIPROT ID#>>Q8TF40
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

folliculin interacting protein 1 interacts with:

• claspin
  folliculin
  folliculin interacting protein 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.