EDA2R, ectodysplasin A2 receptor

EDA2R, ectodysplasin A2 receptor

• The protein encoded by this gene is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains cysteine-rich repeats and a single transmembrane domain. This protein binds to the EDA-A2 isoform of ectodysplasin, which plays an important role in maintenance of hair and teeth. Alternatively spliced transcript variants encodes distinct protein isoforms. [provided by RefSeq, Apr 2016]

• Gene Synonyms (tumor necrosis factor receptor superfamily member 27, EDA-A2 receptor, X-linked ectodysplasin-A2 receptor, ectodysplasin A2 isoform receptor, tumor necrosis factor receptor superfamily member XEDAR, EDA-A2R, EDAA2R, TNFRSF27, XEDAR,)
• NCBI Gene ID: 60401
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B4DQY6
  UNIPROT ID#>>Q9HAV5
  UNIPROT ID#>>B2RBZ9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ectodysplasin A2 receptor interacts with:

• anterior gradient 3, protein disulphide isomerase family member
  ectodysplasin A2 receptor
  hydroxysteroid dehydrogenase like 1
  jagunal homolog 1
  small transmembrane regulator of ion transport 1
  transmembrane protein 262

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.