JAGN1, jagunal homolog 1

JAGN1, jagunal homolog 1

• The protein encoded by this gene is a transmembrane protein. It functions in the early secretory pathway and is necessary for neutrophil differentiation and survival. Mutations in this gene result in severe congenital neutropenia. [provided by RefSeq, Oct 2014]

• Gene Synonyms (protein jagunal homolog 1, GL009, SCN6,)
• NCBI Gene ID: 84522
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8N5M9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

jagunal homolog 1 interacts with:

• ADP ribosylation factor like GTPase 13B
  butyrophilin like 9
  calcium homeostasis modulator family member 6
  cAMP responsive element binding protein 3 like 1
  chromosome 4 open reading frame 3
  CKLF like MARVEL transmembrane domain containing 5
  C-type lectin domain family 12 member B
  C-type lectin domain family 4 member D
  cytochrome c oxidase assembly factor COX20
  family with sequence similarity 177 member A1
  family with sequence similarity 209 member A
  FERM domain containing 3
  fibronectin type III domain containing 9
  G protein-coupled receptor 152
  GTPase, IMAP family member 1
  hydroxysteroid 17-beta dehydrogenase 13
  KASH domain containing 5
  killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3
  LEM domain containing 1
  LHFPL tetraspan subfamily member 5
  mitochondrial translational initiation factor 3
  receptor transporter protein 2
  reticulophagy regulator family member 3
  SLAM family member 6
  small integral membrane protein 1 (Vel blood group)
  small integral membrane protein 19
  stomatin like 3
  translocase of inner mitochondrial membrane 23
  transmembrane inner ear
  transmembrane protein 120B
  transmembrane protein 128
  transmembrane protein 199
  transmembrane protein 207
  transmembrane protein 242
  transmembrane protein 52B
  transmembrane protein 65
  t-SNARE domain containing 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.