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PJA1, praja ring finger ubiquitin ligase 1

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PJA1, praja ring finger ubiquitin ligase 1

  • This gene encodes an enzyme that has E2-dependent E3 ubiquitin-protein ligase activity. This enzyme belongs to a class of ubiquitin ligases that include a RING finger motif, and it can interact with the E2 ubiquitin-conjugating enzyme UbcH5B. This gene is located in an area of chromosome X where several X-linked cognitive disability disorders have been associated, and it has also been found as part of a contiguous gene deletion associated with craniofrontonasal syndrome, though a direct link to any disorder has yet to be demonstrated. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]

  • Gene Synonyms (E3 ubiquitin-protein ligase Praja-1, RING finger protein 70, RING-type E3 ubiquitin transferase Praja-1, praja 1, praja ring finger 1, E3 ubiquitin protein ligase, PRAJA1, RNF70,)
  • NCBI Gene ID: 64219
  • Species: Homo sapiens (Human)
  • UNIPROT ID#>>Q8NG27
  • View the NCBI Database for this Gene »

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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