CERK, ceramide kinase

CERK, ceramide kinase

• CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation (Kim et al., 2006 [PubMed 16488390]).[supplied by OMIM, Mar 2008]

• Gene Synonyms (ceramide kinase, acylsphingosine kinase, lipid kinase 4, lipid kinase LK4, LK4, dA59H18.2, dA59H18.3, hCERK,)
• NCBI Gene ID: 64781
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8TCT0
  UNIPROT ID#>>A0A024R4U8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ceramide kinase interacts with:

• cysteine rich tail 1
  HEPACAM family member 2
  hepatitis A virus cellular receptor 2
  ILK associated serine/threonine phosphatase
  keratin associated protein 10-3
  keratin associated protein 1-1
  keratin associated protein 11-1
  keratin associated protein 19-1
  keratin associated protein 19-6
  keratin associated protein 3-1
  keratin associated protein 3-2
  keratin associated protein 6-2
  keratin associated protein 9-2
  melanocortin 2 receptor accessory protein 2
  NBPF member 19
  NHL repeat containing 4
  notch 2 N-terminal like A
  pleckstrin homology and FYVE domain containing 2
  potassium channel tetramerization domain containing 17
  proline rich coiled-coil 2B
  tripartite motif containing 42
  two pore segment channel 2
  UTP4 small subunit processome component
  von Willebrand factor C and EGF domains

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.