CARD11, caspase recruitment domain family member 11

CARD11, caspase recruitment domain family member 11

• The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq, Jul 2008]

• Gene Synonyms (caspase recruitment domain-containing protein 11, CARD-containing MAGUK protein 1, bcl10-interacting maguk protein 3, carma 1, BENTA, BIMP3, CARMA1, IMD11, IMD11A, PPBL,)
• NCBI Gene ID: 84433
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9BXL7
  UNIPROT ID#>>Q8TES3
  UNIPROT ID#>>A0A024R854
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

caspase recruitment domain family member 11 interacts with:

• caspase recruitment domain family member 11
  TGF-beta activated kinase 1 (MAP3K7) binding protein 3

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