LOXL3, lysyl oxidase like 3

LOXL3, lysyl oxidase like 3

• This gene encodes a lysyl oxidase, which likely functions as an amine oxidase and plays a role in the formation of crosslinks in collagens and elastin. Deletion of the related gene in mouse causes neonatal mortality with cleft palate, spine deformity, and defects in collagen organization. A mutation in this gene was found in a family with Stickler syndrome. [provided by RefSeq, Sep 2016]

• Gene Synonyms (lysyl oxidase homolog 3, lysyl oxidase-like protein 3, LOXL,)
• NCBI Gene ID: 84695
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P58215
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

lysyl oxidase like 3 interacts with:

• musashi RNA binding protein 2
  SUMO specific peptidase 5
  VPS26, retromer complex component B

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.