SYNJ1, synaptojanin 1

SYNJ1, synaptojanin 1

• This gene encodes a phosphoinositide phosphatase that regulates levels of membrane phosphatidylinositol-4,5-bisphosphate. As such, expression of this enzyme may affect synaptic transmission and membrane trafficking. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

• Gene Synonyms (synaptojanin-1, inositol 5'-phosphatase (synaptojanin 1), inositol polyphosphate-5-phosphatase G, phosphoinositide 5-phosphatase, synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1, synaptojanin-1, polyphosphoinositide phosphatase, EIEE53, INPP5G, PARK20,)
• NCBI Gene ID: 8867
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A0D9SGJ6
  UNIPROT ID#>>O43426
  UNIPROT ID#>>Q05CZ1
  UNIPROT ID#>>B9EGN3
  UNIPROT ID#>>J3KQV8
  UNIPROT ID#>>C9JFZ1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

synaptojanin 1 interacts with:

• alkB homolog 2, alpha-ketoglutarate dependent dioxygenase
  BICD cargo adaptor 2
  DDB1 and CUL4 associated factor 15
  dynein cytoplasmic 1 light intermediate chain 1
  formin binding protein 4
  G2 and S-phase expressed 1
  protein kinase C and casein kinase substrate in neurons 1
  protein kinase C and casein kinase substrate in neurons 2
  protein kinase C and casein kinase substrate in neurons 3
  SH3 domain binding protein 1
  SH3 domain containing GRB2 like, endophilin B1
  SH3 domain containing kinase binding protein 1
  sorting nexin 9
  trans-golgi network protein 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.