MED21, mediator complex subunit 21

MED21, mediator complex subunit 21

• This gene encodes a member of the mediator complex subunit 21 family. The encoded protein interacts with the human RNA polymerase II holoenzyme and is involved in transcriptional regulation of RNA polymerase II transcribed genes. A pseudogene of this gene is located on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]

• Gene Synonyms (mediator of RNA polymerase II transcription subunit 21, RNA polymerase II holoenzyme component SRB7, RNAPII complex component SRB7, SRB7 suppressor of RNA polymerase B homolog, SRB7, SURB7, hSrb7,)
• NCBI Gene ID: 9412
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024RAW0
  UNIPROT ID#>>Q13503
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

mediator complex subunit 21 interacts with:

• autophagy related 16 like 1
  biogenesis of lysosomal organelles complex 1 subunit 6
  BLOC-1 related complex subunit 6
  cyclin dependent kinase 19
  cytoskeleton associated protein 4
  endonuclease/exonuclease/phosphatase family domain containing 1
  F-box and leucine rich repeat protein 19
  F-box and WD repeat domain containing 7
  glutamate rich 5
  kinesin family member 2C
  mediator complex subunit 10
  mediator complex subunit 11
  mediator complex subunit 12
  mediator complex subunit 12L
  mediator complex subunit 13
  mediator complex subunit 13L
  mediator complex subunit 15
  mediator complex subunit 16
  mediator complex subunit 17
  mediator complex subunit 18
  mediator complex subunit 19
  mediator complex subunit 20
  mediator complex subunit 21
  mediator complex subunit 23
  mediator complex subunit 24
  mediator complex subunit 25
  mediator complex subunit 26
  mediator complex subunit 27
  mediator complex subunit 28
  mediator complex subunit 29
  mediator complex subunit 30
  mediator complex subunit 31
  mediator complex subunit 4
  mediator complex subunit 6
  mediator complex subunit 7
  mediator complex subunit 8
  mediator complex subunit 9
  mitochondrial elongation factor 1
  N(alpha)-acetyltransferase 10, NatA catalytic subunit
  peptidyl-tRNA hydrolase 2
  phosphoprotein membrane anchor with glycosphingolipid microdomains 1
  PPARG coactivator 1 alpha
  pterin-4 alpha-carbinolamine dehydratase 2
  Rac GTPase activating protein 1
  ring finger protein 20
  ring finger protein 40
  RNA polymerase II associated protein 2
  RNA polymerase II subunit M
  saccharopine dehydrogenase (putative)
  scavenger receptor cysteine rich family member with 5 domains
  sperm associated antigen 5
  sphingomyelin phosphodiesterase acid like 3B
  syntaxin 8
  trafficking from ER to golgi regulator
  transcription elongation regulator 1
  tripartite motif containing 72
  UL16 binding protein 2
  vacuolar protein sorting 4B
  vesicle transport through interaction with t-SNAREs 1B
  zinc finger and SCAN domain containing 1
  zinc finger CCCH-type containing 13
  zinc finger protein 655
  zinc metallopeptidase STE24

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.