OLIG2, oligodendrocyte transcription factor 2

OLIG2, oligodendrocyte transcription factor 2

• This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. [provided by RefSeq, Jul 2008]

• Gene Synonyms (oligodendrocyte transcription factor 2, basic domain, helix-loop-helix protein, class B, 1, class B basic helix-loop-helix protein 1, class E basic helix-loop-helix protein 19, human protein kinase C-binding protein RACK17, oligodendrocyte lineage transcription factor 2, oligodendrocyte-specific bHLH transcription factor 2, protein kinase C-binding protein 2, BHLHB1, OLIGO2, PRKCBP2, RACK17, bHLHe19,)
• NCBI Gene ID: 10215
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q13516
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

oligodendrocyte transcription factor 2 interacts with:

• epididymal sperm binding protein 1
  keratin associated protein 12-4
  serine and arginine repetitive matrix 1
  SRY-box transcription factor 8
  taxilin alpha

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.