DENND4A, DENN domain containing 4A

DENND4A, DENN domain containing 4A

• This gene encodes a DENN domain-containing protein that may function as a guanine nucleotide exchange factor that specifically activates ras-related protein Rab-10. This protein also contains a interferon stimulated response element-binding domain and may be involved in regulating the v-myc avian myelocytomatosis viral (MYC) oncogene. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8. [provided by RefSeq, Mar 2016]

• Gene Synonyms (IRLB, MYCPBP, C-myc promoter-binding protein, DENN domain-containing protein 4A, DENN/MADD domain containing 4A, c-myc promoter binding protein,)
• NCBI Gene ID: 10260
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q7Z401
  UNIPROT ID#>>Q05C90
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

DENN domain containing 4A interacts with:

• ankyrin repeat and SOCS box containing 3
  chibby family member 1, beta catenin antagonist
  cingulin
  DENN domain containing 1A
  DENN domain containing 4C
  egl-9 family hypoxia inducible factor 3
  GRB10 interacting GYF protein 1
  inositol polyphosphate-5-phosphatase E
  kinesin family member 13B
  leucine rich repeat and fibronectin type III domain containing 1
  LIM domain and actin binding 1
  LY6/PLAUR domain containing 4
  methyltransferase like 6
  microtubule associated serine/threonine kinase 3
  pleckstrin homology domain containing A4
  potassium channel tetramerization domain containing 3
  protein phosphatase, Mg2+/Mn2+ dependent 1H
  serine and arginine rich splicing factor 12
  SERTA domain containing 1
  signal induced proliferation associated 1 like 1
  SLIT-ROBO Rho GTPase activating protein 2
  T cell leukemia homeobox 3
  testis associated actin remodelling kinase 2
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
  vir like m6A methyltransferase associated
  zinc finger and BTB domain containing 21
  zinc finger protein 638

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.