WARS2, tryptophanyl tRNA synthetase 2, mitochondrial

WARS2, tryptophanyl tRNA synthetase 2, mitochondrial

• Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. This gene encodes the mitochondrial tryptophanyl-tRNA synthetase. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

• Gene Synonyms (NEMMLAS, TrpRS, mtTrpRS, tryptophan--tRNA ligase, mitochondrial, (Mt)TrpRS, tryptophan tRNA ligase 2, mitochondrial,)
• NCBI Gene ID: 10352
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UGM6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

tryptophanyl tRNA synthetase 2, mitochondrial interacts with:

• mitochondrial rRNA methyltransferase 1
  N(alpha)-acetyltransferase 11, NatA catalytic subunit
  required for meiotic nuclear division 5 homolog A
  tRNA methyltransferase 61B
  tryptophanyl tRNA synthetase 2, mitochondrial

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.