CDC42EP2, CDC42 effector protein 2

CDC42EP2, CDC42 effector protein 2

• CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of CDC42. Coexpression of this protein with CDC42 suggested a role of this protein in actin filament assembly and cell shape control. [provided by RefSeq, Aug 2011]

• Gene Synonyms (BORG1, CEP2, cdc42 effector protein 2, CDC42 effector protein (Rho GTPase binding) 2, CRIB-containing BOGR1 protein, binder of Rho GTPases 1,)
• NCBI Gene ID: 10435
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O14613
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

CDC42 effector protein 2 interacts with:

• Cas scaffold protein family member 4
  NME/NM23 family member 7
  ras homolog family member Q
  Rho GTPase activating protein 26
  septin 6
  vir like m6A methyltransferase associated

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.