PFDN6, prefoldin subunit 6

PFDN6, prefoldin subunit 6

• PFDN6 is a subunit of the heteromeric prefoldin complex that chaperones nascent actin (see MIM 102560) and alpha- and beta-tubulin (see MIM 602529 and MIM 191130, respectively) chains pending their transfer to the cytosolic chaperonin containing TCP1 (MIM 186980) (CCT) complex (Hansen et al., 1999 [PubMed 10209023]).[supplied by OMIM, Jul 2010]

• Gene Synonyms (H2-KE2, HKE2, KE-2, PFD6, prefoldin subunit 6, HLA class II region expressed gene KE2, KE2 protein,)
• NCBI Gene ID: 10471
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q5STK2
  UNIPROT ID#>>O15212
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

prefoldin subunit 6 interacts with:

• coiled-coil alpha-helical rod protein 1
  D-dopachrome tautomerase like
  EEF1A lysine methyltransferase 3
  egl-9 family hypoxia inducible factor 3
  F-box protein 2
  ISY1 splicing factor homolog
  KN motif and ankyrin repeat domains 2
  methyl-CpG binding domain protein 3
  POC1 centriolar protein A
  POC1 centriolar protein B
  prefoldin 2
  protein phosphatase 6 regulatory subunit 1
  protein tyrosine phosphatase non-receptor type 21
  regulation of nuclear pre-mRNA domain containing 1B
  ring finger and CCCH-type domains 2
  RNA polymerase I subunit A
  RNA polymerase II associated protein 3
  RNA polymerase III subunit E
  RuvB like AAA ATPase 2
  RuvB-like protein 1
  RuvB-like protein 2
  THAP domain containing 11
  transportin 3
  tubulin alpha 3e
  tubulin, beta 4B class IVB
  vir like m6A methyltransferase associated
  von Hippel-Lindau binding protein 1
  WD repeat containing, antisense to TP73
  WD repeat domain 61
  WD repeat domain 92
  WW domain containing E3 ubiquitin protein ligase 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.