TNPO3, transportin 3

TNPO3, transportin 3

• The protein encoded by this gene is a nuclear import receptor for serine/arginine-rich (SR) proteins such as the splicing factors SFRS1 and SFRS2. The encoded protein has also been shown to be involved in HIV-1 infection, apparently through interaction with the HIV-1 capsid protein. Several protein-coding and non-coding transcript variants have been found for this gene. [provided by RefSeq, Apr 2020]

• Gene Synonyms (transportin-3, imp12, importin 12, limb girdle muscular dystrophy 1F (autosomal dominant), transportin-SR, IPO12, LGMD1F, LGMDD2, MTR10A, TRN-SR, TRN-SR2, TRNSR,)
• NCBI Gene ID: 23534
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B3KMX1
  UNIPROT ID#>>A0A024R794
  UNIPROT ID#>>Q9Y5L0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

transportin 3 interacts with:

• adenylate kinase 7
  arginine and serine rich protein 1
  BRF2 RNA polymerase III transcription initiation factor subunit
  catechol-O-methyltransferase domain containing 1
  CD274 molecule
  charged multivesicular body protein 3
  elaC ribonuclease Z 2
  importin 9
  inner membrane protein, mitochondrial
  islet cell autoantigen 1 like
  keratin associated protein 10-8
  limb development membrane protein 1 like
  LUC7 like
  LY6/PLAUR domain containing 3
  MHC class I polypeptide-related sequence A
  pleckstrin homology domain containing A4
  pleckstrin homology like domain family A member 3
  protein phosphatase 1 regulatory inhibitor subunit 1C
  protein phosphatase 2, regulatory subunit B'', alpha
  proton activated chloride channel 1
  purinergic receptor P2Y12
  RAB5 interacting factor
  RAD18 E3 ubiquitin protein ligase
  scavenger receptor class A member 3
  septin 6
  SIGLEC family like 1
  SMAD specific E3 ubiquitin protein ligase 2
  solute carrier family 15 member 3
  SSX family member 2B
  transmembrane protein 171
  unc-93 homolog B1, TLR signaling regulator
  unk zinc finger
  vasorin
  vir like m6A methyltransferase associated
  V-set and immunoglobulin domain containing 1
  V-set and immunoglobulin domain containing 2
  zinc finger protein 598, E3 ubiquitin ligase

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.