POLG2, DNA polymerase gamma 2, accessory subunit

POLG2, DNA polymerase gamma 2, accessory subunit

• This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.[provided by RefSeq, Sep 2009]

• Gene Synonyms (DNA polymerase subunit gamma-2, mitochondrial, DNA polymerase gamma accessory 55 kDa subunit, mitochondrial DNA polymerase subunit gamma-2, mitochondrial DNA polymerase, accessory subunit, p55, polymerase (DNA directed), gamma 2, accessory subunit, polymerase (DNA) gamma 2, accessory subunit, HP55, MTDPS16, MTPOLB, PEOA4, POLB, POLG-BETA, POLGB,)
• NCBI Gene ID: 11232
• Species: Homo sapiens (Human)
• UNIPROT ID#>>E5KS15
  UNIPROT ID#>>Q9UHN1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

DNA polymerase gamma 2, accessory subunit interacts with:

• activity dependent neuroprotector homeobox
  adaptor related protein complex 4 subunit epsilon 1
  oxysterol binding protein like 1A
  WD repeat containing antisense to TP53

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.