AP4E1, adaptor related protein complex 4 subunit epsilon 1

AP4E1, adaptor related protein complex 4 subunit epsilon 1

• This gene encodes a member of the adaptor complexes large subunit protein family. These proteins are components of the heterotetrameric adaptor protein complexes, which play important roles in the secretory and endocytic pathways by mediating vesicle formation and sorting of integral membrane proteins. The encoded protein is a large subunit of adaptor protein complex-4, which is associated with both clathrin- and nonclathrin-coated vesicles. Disruption of this gene may be associated with cerebral palsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

• Gene Synonyms (AP-4 complex subunit epsilon-1, AP-4 adaptor complex subunit epsilon, adaptor related protein complex 4 epsilon 1 subunit, adaptor-related protein complex AP-4 epsilon, epsilon-adaptin, CPSQ4, SPG51, STUT1,)
• NCBI Gene ID: 23431
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B4DM48
  UNIPROT ID#>>Q9UPM8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

adaptor related protein complex 4 subunit epsilon 1 interacts with:

• golgi integral membrane protein 4
  hook microtubule tethering protein 1
  laminin subunit alpha 1
  pleckstrin homology domain containing A4
  suppressor of variegation 3-9 homolog 2
  TEPSIN adaptor related protein complex 4 accessory protein
  transmembrane protein 17

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