EGLN2, egl-9 family hypoxia inducible factor 2

EGLN2, egl-9 family hypoxia inducible factor 2

• The hypoxia inducible factor (HIF) is a transcriptional complex that is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this post-translational modification. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream RAB4B (RAB4B, member RAS oncogene family) gene. [provided by RefSeq, Feb 2011]

• Gene Synonyms (EIT-6, EIT6, HIF-PH1, HIFPH1, HPH-1, HPH-3, PHD1, prolyl hydroxylase EGLN2, HIF-prolyl hydroxylase 1, egl nine homolog 2, estrogen-induced tag 6, hypoxia-inducible factor prolyl hydroxylase 1, prolyl hydroxylase domain-containing protein 1,)
• NCBI Gene ID: 112398
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R0R2
  UNIPROT ID#>>Q96KS0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

egl-9 family hypoxia inducible factor 2 interacts with:

• egl-9 family hypoxia inducible factor 2
  egl-9 family hypoxia inducible factor 3
  WT1 interacting protein

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.