VSIG4, V-set and immunoglobulin domain containing 4

VSIG4, V-set and immunoglobulin domain containing 4

• This gene encodes a v-set and immunoglobulin-domain containing protein that is structurally related to the B7 family of immune regulatory proteins. The encoded protein may be a negative regulator of T-cell responses. This protein is also a receptor for the complement component 3 fragments C3b and iC3b. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]

• Gene Synonyms (V-set and immunoglobulin domain-containing protein 4, Ig superfamily protein, complement receptor of the immunoglobulin superfamily, protein Z39Ig, CRIg, Z39IG,)
• NCBI Gene ID: 11326
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y279
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

V-set and immunoglobulin domain containing 4 interacts with:

• abhydrolase domain containing 18
  adhesion G protein-coupled receptor L1
  ATPase secretory pathway Ca2+ transporting 1
  CDC42 small effector 2
  DENN domain containing 6A
  diacylglycerol lipase beta
  fatty acyl-CoA reductase 2
  fetal and adult testis expressed 1
  integrator complex subunit 4
  integrator complex subunit 7
  jagunal homolog 1
  kelch domain containing 3
  kinase D interacting substrate 220
  mitochondrial carrier 1
  mitochondrial fission process 1
  pentatricopeptide repeat domain 2
  polypeptide N-acetylgalactosaminyltransferase 11
  protein kinase N3
  RAB18, member RAS oncogene family
  semaphorin 4C
  SH3 domain binding protein 4
  solute carrier family 25 member 23
  tigger transposable element derived 5
  trans-golgi network vesicle protein 23 homolog C
  translocase of inner mitochondrial membrane 29
  tripartite motif containing 72
  TRPM8 channel associated factor 2
  uroplakin 3B like 1
  WD repeat domain 44
  zinc finger DHHC-type palmitoyltransferase 6

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.