TNFRSF13C, TNF receptor superfamily member 13C

TNFRSF13C, TNF receptor superfamily member 13C

• B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. [provided by RefSeq, Jul 2008]

• Gene Synonyms (BAFF-R, BAFFR, BROMIX, CD268, CVID4, prolixin, tumor necrosis factor receptor superfamily member 13C, B cell-activating factor receptor, BAFF receptor, BLyS receptor 3,)
• NCBI Gene ID: 115650
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q96RJ3
  UNIPROT ID#>>Q5H8V1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

TNF receptor superfamily member 13C interacts with:

• TNF receptor superfamily member 13C

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