Trim24, tripartite motif-containing 24

Trim24, tripartite motif-containing 24

• The protein encoded by this gene is part of the tripartite-motif containing family (TRIM), which are typified by the RING, B-box type 1, B-box type 2, and coiled-coil region domains. This protein, which also contains a PHD/TTC finger and bromodomain important for regulating nuclear receptors and binding chromatin, has important roles in differentiation, development, and tissue homeostasis. This protein has been reported to regulate the activity of the tumor suppressor p53 and of the retinoic acid receptor. A translocation event between this gene and Braf transforming gene, which results in the fusion protein T18, has been reported in hepatocellular carcinomas. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jan 2013]

• (No alternate names found)
• NCBI Gene ID: 21848
• Species: Mus musculus (Mouse)
• UNIPROT ID#>>E9Q1U8
  UNIPROT ID#>>Q3V0H4
  UNIPROT ID#>>Q64127
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

tripartite motif-containing 24 interacts with:

• mitochondrial ribosomal protein S31
  nuclear receptor interacting protein 1
  phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
  SERTA domain containing 1
  tripartite motif containing 33
  tripartite motif-containing 24

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.