TFEC, transcription factor EC

TFEC, transcription factor EC

• This gene encodes a member of the micropthalmia (MiT) family of basic helix-loop-helix leucine zipper transcription factors. MiT transcription factors regulate the expression of target genes by binding to E-box recognition sequences as homo- or heterodimers, and play roles in multiple cellular processes including survival, growth and differentiation. The encoded protein is a transcriptional activator of the nonmuscle myosin II heavy chain-A gene, and may also co-regulate target genes in osteoclasts as a heterodimer with micropthalmia-associated transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]

• Gene Synonyms (transcription factor EC, class E basic helix-loop-helix protein 34, TCFEC, TFE-C, TFEC-L, TFECL, bHLHe34, hTFEC-L,)
• NCBI Gene ID: 22797
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O14948
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

transcription factor EC interacts with:

• defensin beta 127
  developmental pluripotency-associated 3
  lysophosphatidic acid receptor 3
  NSF attachment protein beta
  single-pass membrane protein with coiled-coil domains 4
  transcription factor EC
  zinc finger matrin-type 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.