RPIA, ribose 5-phosphate isomerase A

RPIA, ribose 5-phosphate isomerase A

• The protein encoded by this gene is an enzyme, which catalyzes the reversible conversion between ribose-5-phosphate and ribulose-5-phosphate in the pentose-phosphate pathway. This gene is highly conserved in most organisms. The enzyme plays an essential role in the carbohydrate metabolism. Mutations in this gene cause ribose 5-phosphate isomerase deficiency. A pseudogene is found on chromosome 18. [provided by RefSeq, Mar 2010]

• Gene Synonyms (RPI, RPIAD, ribose-5-phosphate isomerase, phosphoriboisomerase, ribose 5-phosphate epimerase,)
• NCBI Gene ID: 22934
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P49247
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ribose 5-phosphate isomerase A interacts with:

• ATP synthase mitochondrial F1 complex assembly factor 2
  centromere protein P
  chromosome 14 open reading frame 119
  desert hedgehog signaling molecule
  DNA damage inducible transcript 4 like
  endoplasmic reticulum protein 44
  forkhead box P2
  golgi reassembly stacking protein 2
  heat shock protein family B (small) member 8
  ligand of numb-protein X 1
  lysine demethylase 6B
  microtubule affinity regulating kinase 4
  NGG1 interacting factor 3 like 1
  N-terminal glutamine amidase 1
  ribose 5-phosphate isomerase A
  ring finger protein 208
  thioredoxin 2
  transient receptor potential cation channel subfamily V member 5
  vesicle trafficking 1
  WD repeat domain 5B

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.