KDM4C, lysine demethylase 4C

KDM4C, lysine demethylase 4C

• This gene is a member of the Jumonji domain 2 (JMJD2) family. The encoded protein is a trimethylation-specific demethylase, and converts specific trimethylated histone residues to the dimethylated form. This enzymatic action regulates gene expression and chromosome segregation. Chromosomal aberrations and changes in expression of this gene may be found in tumor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

• Gene Synonyms (GASC1, JHDM3C, JMJD2C, TDRD14C, lysine-specific demethylase 4C, JmjC domain-containing histone demethylation protein 3C, [histone H3]-trimethyl-L-lysine(9) demethylase 4C, gene amplified in squamous cell carcinoma 1 protein, jumonji domain-containing protein 2C, lysine (K)-specific demethylase 4C, tudor domain containing 14C,)
• NCBI Gene ID: 23081
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9H3R0
  UNIPROT ID#>>B0QZ60
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

lysine demethylase 4C interacts with:

• bromodomain containing 4
  H3 clustered histone 14
  lysine demethylase 4C
  vir like m6A methyltransferase associated

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.