MLYCD, malonyl-CoA decarboxylase

MLYCD, malonyl-CoA decarboxylase

• The product of this gene catalyzes the breakdown of malonyl-CoA to acetyl-CoA and carbon dioxide. Malonyl-CoA is an intermediate in fatty acid biosynthesis, and also inhibits the transport of fatty acyl CoAs into mitochondria. Consequently, the encoded protein acts to increase the rate of fatty acid oxidation. It is found in mitochondria, peroxisomes, and the cytoplasm. Mutations in this gene result in malonyl-CoA decarboyxlase deficiency. [provided by RefSeq, Jul 2008]

• Gene Synonyms (malonyl-CoA decarboxylase, mitochondrial, malonyl coenzyme A decarboxylase, MCD,)
• NCBI Gene ID: 23417
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O95822
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

malonyl-CoA decarboxylase interacts with:

• aarF domain containing kinase 1
  coenzyme Q6, monooxygenase
  FYVE and coiled-coil domain autophagy adaptor 1
  protocadherin alpha 10
  protocadherin alpha 12
  protocadherin alpha 3
  protocadherin gamma subfamily A, 5
  sorting nexin 9
  UBA like domain containing 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.