TMIE, transmembrane inner ear

TMIE, transmembrane inner ear

• This gene encodes a transmembrane inner ear protein. Studies in mouse suggest that this gene is required for normal postnatal maturation of sensory hair cells in the cochlea, including correct development of stereocilia bundles. This gene is one of multiple genes responsible for recessive non-syndromic deafness (DFNB), also known as autosomal recessive nonsyndromic hearing loss (ARNSHL), the most common form of congenitally acquired inherited hearing impairment. [provided by RefSeq, Mar 2009]

• Gene Synonyms (transmembrane inner ear expressed protein, transmembrane inner ear protein, DFNB6,)
• NCBI Gene ID: 259236
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8NEW7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

transmembrane inner ear interacts with:

• keratin associated protein 10-8
  keratin associated protein 12-3
  NBPF member 19
  notch 2 N-terminal like A
  phospholipid phosphatase 6
  transmembrane inner ear
  transmembrane protein 242
  transmembrane protein with metallophosphoesterase domain

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.