ACOT11, acyl-CoA thioesterase 11

ACOT11, acyl-CoA thioesterase 11

• This gene encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low temperatures and repressed by warm temperatures. Higher levels of expression of the mouse homolog has been found in obesity-resistant mice compared with obesity-prone mice, suggesting a role of acyl-CoA thioesterase 11 in obesity. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010]

• Gene Synonyms (acyl-coenzyme A thioesterase 11, START domain containing 14, StAR-related lipid transfer (START) domain containing 14, acyl-CoA thioester hydrolase 11, adipose-associated thioesterase, brown fat-inducible thioesterase, palmitoyl-coenzyme A thioesterase, thioesterase superfamily member 1, thioesterase, adipose associated, BFIT, STARD14, THEA, THEM1,)
• NCBI Gene ID: 26027
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8WXI4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

acyl-CoA thioesterase 11 interacts with:

• acyl-CoA thioesterase 11
  acyl-CoA thioesterase 12
  C2 calcium dependent domain containing 6
  calcium binding protein 5
  exosome component 5
  gem nuclear organelle associated protein 6
  histone deacetylase 7
  tektin 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.