IL36RN, interleukin 36 receptor antagonist

IL36RN, interleukin 36 receptor antagonist

• The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine was shown to specifically inhibit the activation of NF-kappaB induced by interleukin 1 family, member 6 (IL1F6). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]

• Gene Synonyms (interleukin-36 receptor antagonist protein, IL-1 related protein 3, IL-1F5 (IL-1HY1, FIL1-delta, IL-1RP3, IL-1L1, IL-1-delta), IL-1ra homolog 1, IL1F5 (Canonical product IL-1F5a), interleukin 1 family, member 5 (delta), interleukin-1 HY1, interleukin-1 receptor antagonist homolog 1, interleukin-1-like protein 1, FIL1, FIL1(DELTA), FIL1D, IL-36Ra, IL1F5, IL1HY1, IL1L1, IL1RP3, IL36RA, PSORP, PSORS14,)
• NCBI Gene ID: 26525
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R518
  UNIPROT ID#>>Q9UBH0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

interleukin 36 receptor antagonist interacts with:

• adaptor related protein complex 3 subunit mu 1
  calcium release activated channel regulator 2B
  cyclin dependent kinase 15
  DNA damage inducible transcript 4 like
  heterogeneous nuclear ribonucleoprotein L like
  inhibitor of CDK, cyclin A1 interacting protein 1
  interleukin 1 receptor associated kinase 4
  single stranded DNA binding protein 4
  TBC1 domain family member 22B
  ubiquitin like 4B
  zinc finger protein 512B
  zinc finger with KRAB and SCAN domains 4

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.