GLS2, glutaminase 2

GLS2, glutaminase 2

• The protein encoded by this gene is a mitochondrial phosphate-activated glutaminase that catalyzes the hydrolysis of glutamine to stoichiometric amounts of glutamate and ammonia. Originally thought to be liver-specific, this protein has been found in other tissues as well. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013]

• Gene Synonyms (glutaminase liver isoform, mitochondrial, L-glutamine amidohydrolase, breast cell glutaminase, glutaminase 2 (liver, mitochondrial), glutaminase I, phosphate-activated glutaminase, phosphate-dependent glutaminase, GA, GLS, LGA, hLGA,)
• NCBI Gene ID: 27165
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A087X004
  UNIPROT ID#>>Q9UI32
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

glutaminase 2 interacts with:

• phosphoprotein membrane anchor with glycosphingolipid microdomains 1
  Tax1 binding protein 3
  XIAP associated factor 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.