EML4, EMAP like 4

EML4, EMAP like 4

• This gene is a member of the echinoderm microtubule associated protein-like family. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants. [provided by RefSeq, Jan 2015]

• Gene Synonyms (echinoderm microtubule-associated protein-like 4, echinoderm microtubule associated protein like 4, restrictedly overexpressed proliferation-associated protein, ropp 120, C2orf2, ELP120, EMAP-4, EMAPL4, ROPP120,)
• NCBI Gene ID: 27436
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B5MBZ0
  UNIPROT ID#>>Q9HC35
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

EMAP like 4 interacts with:

• autophagy related 16 like 1
  EMAP like 4
  NIMA (never in mitosis gene a)-related expressed kinase 9
  NIMA related kinase 7
  spindle and centriole associated protein 1
  tubulin beta 2B class IIb
  tubulin beta class I

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.