ID1, inhibitor of DNA binding 1, HLH protein

ID1, inhibitor of DNA binding 1, HLH protein

• The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. The encoded protein has no DNA binding activity and therefore can inhibit the DNA binding and transcriptional activation ability of basic HLH proteins with which it interacts. This protein may play a role in cell growth, senescence, and differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (DNA-binding protein inhibitor ID-1, class B basic helix-loop-helix protein 24, dJ857M17.1.2 (inhibitor of DNA binding 1, dominant negative helix-loop-helix protein), inhibitor of DNA binding 1, dominant negative helix-loop-helix protein, inhibitor of differentiation 1, ID, bHLHb24,)
• NCBI Gene ID: 3397
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P41134
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

inhibitor of DNA binding 1, HLH protein interacts with:

• achaete-scute family bHLH transcription factor 3
  adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
  beta-1,4-galactosyltransferase 7
  BUD31 homolog
  calcium/calmodulin dependent serine protein kinase
  chromodomain helicase DNA binding protein 1 like
  coiled-coil domain containing 9
  DNA methyltransferase 3 like
  double PHD fingers 2
  elongin C
  endoplasmic reticulum protein 44
  fizzy and cell division cycle 20 related 1
  inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
  interferon gamma inducible protein 16
  MAPK interacting serine/threonine kinase 1
  membrane palmitoylated protein 1
  mesogenin 1
  myogenic differentiation 1
  myogenic factor 5
  myogenic factor 6
  myogenin
  proteasome 26S subunit, non-ATPase 4
  proteasome 26S subunit, non-ATPase 5
  protection of telomeres 1
  protein inhibitor of activated STAT 1
  protein phosphatase 2 catalytic subunit alpha
  Ras association domain family member 1
  sequestosome 1
  SMAD specific E3 ubiquitin protein ligase 2
  suppressor of variegation 3-9 homolog 1
  syntaxin binding protein 1
  thioredoxin like 4A
  THO complex 6
  TNF receptor associated factor 6
  transcription factor 12
  transcription factor 3
  transcription factor 4
  ubiquitin specific peptidase 15
  von Hippel-Lindau tumor suppressor
  zinc finger CCCH-type containing 13

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.