THOC6, THO complex 6

THOC6, THO complex 6

• This gene encodes a subunit of the multi-protein THO complex, which is involved in coordination between transcription and mRNA processing. The THO complex is a component of the TREX (transcription/export) complex, which is involved in transcription and export of mRNAs. A missense mutation in this gene is associated with a neurodevelopmental disorder called Beaulieu-Boycott-Innes syndrome. [provided by RefSeq, Dec 2016]

• Gene Synonyms (THO complex subunit 6 homolog, WD repeat domain 58, WD repeat-containing protein 58, functional spliceosome-associated protein 35, WDR58, fSAP35,)
• NCBI Gene ID: 79228
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q86W42
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

THO complex 6 interacts with:

• serine and arginine-rich splicing factor 1
  THO complex 3
  THO complex 7
  tripartite motif containing 55
  zinc finger protein 326

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.