IGF1, insulin like growth factor 1

IGF1, insulin like growth factor 1

• The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Sep 2015]

• Gene Synonyms (insulin-like growth factor I, insulin-like growth factor 1 (somatomedin C), insulin-like growth factor IB, mechano growth factor, somatomedin-C, IGF, IGF-I, IGFI, MGF,)
• NCBI Gene ID: 3479
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q13429
  UNIPROT ID#>>Q5U743
  UNIPROT ID#>>P05019
  UNIPROT ID#>>Q59GC5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

insulin like growth factor 1 interacts with:

• BTG3 associated nuclear protein
  cellular communication network factor 3
  enkurin domain containing 1
  immunoglobulin superfamily member 1
  insulin like growth factor 1 receptor
  insulin like growth factor binding protein 1
  insulin like growth factor binding protein 2
  insulin like growth factor binding protein 3
  insulin like growth factor binding protein 4
  insulin like growth factor binding protein 5
  insulin like growth factor binding protein 6
  insulin like growth factor binding protein 7
  insulin like growth factor binding protein acid labile subunit
  makorin ring finger protein 3
  mesoderm development LRP chaperone
  SRY-box transcription factor 4
  suppressor of cytokine signaling 1
  transcription elongation factor A N-terminal and central domain containing
  transferrin
  zinc finger DHHC-type palmitoyltransferase 18
  zinc finger DHHC-type palmitoyltransferase 23

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.