IGFALS, insulin like growth factor binding protein acid labile subunit

IGFALS, insulin like growth factor binding protein acid labile subunit

• The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

• Gene Synonyms (insulin-like growth factor-binding protein complex acid labile subunit, insulin-like growth factor binding protein complex acid labile chain, ACLSD, ALS,)
• NCBI Gene ID: 3483
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P35858
  UNIPROT ID#>>Q8TAY0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

insulin like growth factor binding protein acid labile subunit interacts with:

• insulin like growth factor binding protein 3
  insulin like growth factor binding protein 5
  programmed cell death 6
  vir like m6A methyltransferase associated

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.