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PDCD6, programmed cell death 6

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PDCD6, programmed cell death 6

  • This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5. [provided by RefSeq, May 2012]

  • Gene Synonyms (programmed cell death protein 6, apoptosis-linked gene 2 protein, apoptosis-linked gene 2 protein homolog, probable calcium-binding protein ALG-2, ALG-2, ALG2, PEF1B,)
  • NCBI Gene ID: 10016
  • Species: Homo sapiens (Human)
  • UNIPROT ID#>>A0A024QZ42
    UNIPROT ID#>>Q53FC3
    UNIPROT ID#>>A0A087WZ38
    UNIPROT ID#>>O75340
  • View the NCBI Database for this Gene »

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

programmed cell death 6 interacts with:

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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